Panama is a club where the big names from the DJ world are programmed. It attracts large crowds of young urban people and is located a bit out of the center in a renovated industrial building (but still just a 5 minute tram ride from central station).
Be sure to check out the website before you go, as the nights have different programs. Thursday is students night, with a valid students card you might get in for free or at least quite cheaply (5 euro). On other nights prices vary from 10 to 20 euro. It is wise to buy your entrance tickets beforehand as the place gets sold out often. You can buy tickets online or at the AUB shop Leidse square.
Besides the club there is also a bar and restaurant. Sometimes you can get discounted or free tickets for the club if you eat in the restaurant (ask the waiter or call them). Dinner costs around 20 to 30 euro a person.